Agitation is a crucial problem in the care of patients with Alzheimer's dis
ease. Behaviors such as wandering, physical and verbal aggression, resistin
g care, and arguing ape common and frequently lead to caregiver burnout and
patient institutionalization. While clinical suggestions to help caregiver
s deal with such problems are plentiful, no standardized approach has been
published nor are controlled clinical trials available. This article presen
ts a standardized, social-learning-based, behavioral approach to the treatm
ent of agitation in patients with dementia. It describes a multisite, rando
mized, controlled clinical trial designed to evaluate this approach and ill
ustrates the use of this approach in four cases from three different sites.