Extracting and visualizing matrix-assisted laser desorption/ionization time-of-flight mass spectral fingerprints

Citation
Kh. Jarman et al., Extracting and visualizing matrix-assisted laser desorption/ionization time-of-flight mass spectral fingerprints, RAP C MASS, 13(15), 1999, pp. 1586-1594
Citations number
14
Categorie Soggetti
Spectroscopy /Instrumentation/Analytical Sciences
Journal title
RAPID COMMUNICATIONS IN MASS SPECTROMETRY
ISSN journal
09514198 → ACNP
Volume
13
Issue
15
Year of publication
1999
Pages
1586 - 1594
Database
ISI
SICI code
0951-4198(1999)13:15<1586:EAVMLD>2.0.ZU;2-P
Abstract
We have developed a method for constructing and extracting matrix-assisted laser desorption/ionization (MALDI) fingerprints, This method is fully auto mated and statistically based, allowing a large number of spectra to be ana lyzed at a time in an objective manner. This method can be used to extract the fingerprint of a particular analyte from a spectrum containing multiple analytes, Therefore, this method lends itself well to real-world applicati ons where samples to be analyzed are likely to be impure, We illustrate thi s method on experimental results from a series of studies of E. coli and B. atrophaeus MALDI time-of-flight mass spectrometry (TOFMS) fingerprints. Co pyright (C) 1999 John Whey & Sons, Ltd.