SOLPRO - THEORY AND COMPUTER-PROGRAM FOR THE PREDICTION OF SOLUTION PROPERTIES OF RIGID MACROMOLECULES AND BIOPARTICLES

Single-valued hydrodynamic coefficients of a rigid particle can be cal culated from existing theories and computer programs for either bead m odels or ellipsoids. Starting from these coefficients, we review the p rocedures for the calculation of complex solution properties depending on rotational diffusion, such as the decays of electric birefringence and fluorescence anisotropy. We also describe the calculation of the scattering form factor of bead models. The hydrodynamic coefficients a nd solution properties can be combined to give universal, shape-depend ent functions, which were initially intended for ellipsoidal particles , and are extended here for the most general case. We have implemented all these developments in a new computer program, SOLPRO, for calcula tion of SOLution PROperties, which can be linked to existing software for bead models or ellipsoids.