Bicyclo[3.2.1]octanes via McMurry couplings

Authors
Hong, BC Chin, SF
Citation
Bc. Hong et Sf. Chin, Bicyclo[3.2.1]octanes via McMurry couplings, SYN COMMUN, 29(18), 1999, pp. 3097-3106
Citations number
39
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
SYNTHETIC COMMUNICATIONS
ISSN journal
00397911 → ACNP
Volume
29
Issue
18
Year of publication
1999
Pages
3097 - 3106
Database
ISI
SICI code
0039-7911(1999)29:18<3097:BVMC>2.0.ZU;2-N
Abstract
A novel approach to the synthesis of bicyclo[3.2.1]octane systems is descri bed. The key step involves the McMurry coupling of ketoaldehyde 7 which lea ds to the bridgehead dihydroxybicyclo[3.2.1]octane 8.