CH/pi interaction in the conformation of organic compounds. A database study

A study was carried out, with use of the Cambridge Structural Database, to examine the role of CH/pi interaction in the conformation of organic compou nds. A number of short intramolecular CH/pi distances have been disclosed i n the crystal structure of these compounds. The structure was inspected to know whether the crystal conformation is a consequence of the so-called pac king forces, or the CH/pi interaction plays a role. The result has demonstr ated that the CH/pi interaction plays an appreciable role in controlling th e conformation of organic compounds. (C) 1999 Elsevier Science Ltd. All rig hts reserved.