Synthesis of PI(3,4,5)P-3 with unsaturated and saturated fatty acid chains

Authors
Watanabe, Y Nakatomi, M
Citation
Y. Watanabe et M. Nakatomi, Synthesis of PI(3,4,5)P-3 with unsaturated and saturated fatty acid chains, TETRAHEDRON, 55(32), 1999, pp. 9743-9754
Citations number
29
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON
ISSN journal
00404020 → ACNP
Volume
55
Issue
32
Year of publication
1999
Pages
9743 - 9754
Database
ISI
SICI code
0040-4020(19990806)55:32<9743:SOPWUA>2.0.ZU;2-K
Abstract
Synthesis of three PI(3,4,5)P(3)s, sn-1-O-stearoyl-sn-2-O-arachidonoyl, ste aroyl-linolenoyl, and distearoyl phosphatidyl-myo-inositol 3,4,5-trisphosph ate with the natural configuration for the arachidonoyl version was establi shed by employing 9-fluorenylmethyl-protected phosphate derivatives. (C) 19 99 Elsevier Science Ltd. All rights reserved.