Oxazolidinone to succinamide: a novel rearrangement reaction

Authors
Cheng, MY De, B Wahl, CT Almstead, NG Natchus, MG Pikul, S
Citation
My. Cheng et al., Oxazolidinone to succinamide: a novel rearrangement reaction, TETRAHEDR L, 40(33), 1999, pp. 5975-5977
Citations number
5
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
40
Issue
33
Year of publication
1999
Pages
5975 - 5977
Database
ISI
SICI code
0040-4039(19990813)40:33<5975:OTSANR>2.0.ZU;2-S
Abstract
During the course of an investigative work with a monosubstituted succinic acid half-ester tethered to a chiral oxazolidinone, an unexpected disubstit uted succinimide was obtained with a high degree of stereoselectivity as th e major product. Subsequent investigative work confirmed the structure and further defined the scope of this rearrangement reaction. (C) 1999 Elsevier Science Ltd. All rights reserved.