A general method for the alkaline cleavage of enolisable ketones

Authors
Zabjek, A Petric, A
Citation
A. Zabjek et A. Petric, A general method for the alkaline cleavage of enolisable ketones, TETRAHEDR L, 40(33), 1999, pp. 6077-6078
Citations number
15
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
40
Issue
33
Year of publication
1999
Pages
6077 - 6078
Database
ISI
SICI code
0040-4039(19990813)40:33<6077:AGMFTA>2.0.ZU;2-A
Abstract
An efficient method is described for the cleavage of enolisable aryl methyl and aryl ethyl ketones using an excess of KOH in DMF at an elevated temper ature. It presents a general hydrolytic method yielding aromatic carboxylic acids, and is complementary to the widely used oxidative methods for keton e cleavage. (C) 1999 Elsevier Science Ltd. All rights reserved.