Synthesis of oxazolinyl aziridines

Authors
Florio, S Troisi, L Capriati, V Ingrosso, G
Citation
S. Florio et al., Synthesis of oxazolinyl aziridines, TETRAHEDR L, 40(33), 1999, pp. 6101-6104
Citations number
28
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
40
Issue
33
Year of publication
1999
Pages
6101 - 6104
Database
ISI
SICI code
0040-4039(19990813)40:33<6101:SOOA>2.0.ZU;2-T
Abstract
Aziridinyllithiums 4a and 4b, which are stable at low temperature, can be g enerated by deprotonation of 3a and 3b. Oxazolinyl aziridines 5a-j and 6a-b have been prepared by the reaction of oxazolinyl aziridinyllithiums 4a and 4b with electrophiles. Aziridines 6c and 6d were, instead, synthesized by a Darzens-like reaction from 2-(1-chloroethyl)-2-oxazoline 1b. (C) 1999 Els evier Science Ltd. All rights reserved.