Syntheses of 5 '-O-glycosylnucleosides

Authors
Liu, ZJ Zhou, M Min, JM Zhang, LH
Citation
Zj. Liu et al., Syntheses of 5 '-O-glycosylnucleosides, TETRAHEDR-A, 10(11), 1999, pp. 2119-2127
Citations number
22
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON-ASYMMETRY
ISSN journal
09574166 → ACNP
Volume
10
Issue
11
Year of publication
1999
Pages
2119 - 2127
Database
ISI
SICI code
0957-4166(19990604)10:11<2119:SO5'>2.0.ZU;2-7
Abstract
A general synthetic approach to 2,3-unsaturated glycosides connecting with nucleosides involving Ferrier rearrangements of glycals is discussed. The n ew compounds were identified by NMR and MS (HRFAB(+)). The hydroxylation of the resulting 2,3-unsaturated glycosides was completed using OsO4 to give 5'-O-glycosylnucleosides in good yield. (C) 1999 Elsevier Science Ltd. All rights reserved.