Aim: To assess the value of the renal resistive index (RI) in evaluating re
nal perfusion in children with vesicoureteral reflux (VUR). Method: We inve
stigated 92 kidneys in 46 children with VUR with a mean age of 6 +/- 4 year
s. The RI was measured at the level of the interlobar-/arcuate-arteries usi
ng a color Doppler unit Acuson 128 XP/10 (Mountain View, Gal.). The results
of the RI-measurement were correlated to the findings in renal scintigraph
y. Results: Children with VUR grade I-III showed RI-values less than the no
rmal physiological upper limit of 0.7. Patients with VUR grade IV-V demonst
rated a significant increased RI-value of 0.77 +/- 0.07 (p < 0.0001). The c
orrelation of the RI-measurements with the scintigraphic findings revealed
a correlation-coefficient of r(2) = 0.61. Conclusion: Changes of renal perf
usion were only found in high-grade VUR, demonstrating a good correlation w
ith the scintigraphic findings. Therefore color Doppler ultrasound seems to
be helpful in the follow-up of patients with high-grade reflux.