We have developed an otoneurological expert system (ONE) to aid the diagnos
tics of vertigo, to assist reaching and to implement a ci;database for rese
arch. The ONE database is set to harvest data on patient history, signs and
test results nesessary for diagnostic work with vertiginous patients. A me
thod based on pattern recognition was used in the reasoning process. Questi
on about symptoms, signs and test results are weighted and scored for each
disease and the most likely disease is recognized from defined disease prof
iles. PI;Missing information and uncertainties are solved with a method res
embling fuzzy logic. ONE was validated by comparing diagnoses assessed bq p
hysicians with those provided by the system. It proved to be a valid decisi
on-maker by solving 65% of the cases correctly, while the phisicians mean w
as 69%. To improve ONE further, a follow-up should be implemented for the p
atients. since diagnosing sudden deafness and Meniere's disease during the
first visit is often impossible. We aim to obtain new information, on disea
ses involving vertigo by applying adaptive computer applications, such as g
enetic algorithms. to the reasoning process.