Fetal alcohol syndrome (FAS) is an important cause of mental retardation an
d developmental disabilities. A population based screening tool would allow
for early diagnosis and entry into intervention programs. The aim of the s
tudy was to develop a brief screening tool for use in population-based sett
ings to improve the identification of children with FAS. The FAS Screen was
developed and tested in six sites. These were sites that served children a
nd all were located in North Dakota. Screening was completed on 1013 childr
en, 65 were found to have a positive screening score and were referred for
further investigation. Forty were seen for evaluation by a medical genetici
st and six were diagnosed with FAS. The estimated values for the screening
tool were: specificity 94.1%, sensitivity 100%, positive predictive value 9
.1% and negative predictive value 100%. The cost of screening was $13.00 pe
r child and the cost per case identified was $4,100. The FAS Screen is a br
ief screening test with acceptable performance characteristics and is cost
effective.