Gs. Kalra et al., Transcatheter device closure of ventricular septal defects: Immediate results and intermediate-term follow-up, AM HEART J, 138(2), 1999, pp. 339-344
Citations number
20
Categorie Soggetti
Cardiovascular & Respiratory Systems","Cardiovascular & Hematology Research
Background Transcatheter closure is an accepted mode of treatment in select
ed cases of congenital heart disease. lately, this technology has been appl
ied to closure of ventricular septal defect (VSD).
Methods and Results We performed percutaneous transcatheter closure of VSD
in 30 patients. The location of VSD was perimembranous in 28 patients and m
uscular trabecular in 2. Two (7%) patients also had left ventricular-right
atrial communication. There were 17 male subjects and 13 female subjects, w
ith an age range of 5.5 to 33 years (mean +/- SD, 12.9 +/- 5.7; median 12.2
). The diameter of VSD ranged from 3 to 8 mm (mean +/- SD 4.7 +/- 1.3; medi
an 4.5). In 5 (17%) patients, the pulmonary to systemic blood flow (Qp/Qs)
was greater than or equal to 2.1 (range 2.0 to 2.6). The defect was at leas
t 6 or 8 mm from the aortic valve in patients in whom a 12- or 17-mm Rashki
nd double umbrella device was deployed, respectively. In patient the defect
was closed with a detachable stainless steel coil, size 8 mm, with 4 loops
(8 x 4). The devices were successfully deployed in 87% of patients. In 6 (
20%) patients, the procedure had to be repeated primarily because of the us
e of undersized umbrella deices. Unsuccessful deployment of the device occu
rred in 4 (13%) patients. In one of these procedures, the coil embolized to
the left pulmonary artery, and it was successfully retrieved. A minimal re
sidual shunt seen as a thin streak on transthoracic color flow mapping pers
isted in 8 (30%) patients, which remained unchanged over a follow-vp period
of 5 to 28 (171 +/- 6.4) months. Both patients with left ventricular/right
atrial communication showed complete abolition of the shunt. No patient de
veloped new-onset aortic or tricuspid regurgitation qr intravascular hemoly
sis. At follow-up, no patient had developed infective endocarditis, bundle
branch block, or late valvular insufficiency.
Conclusions Transcatheter closure is safe and efficacious in selected cases
of perimembranous and muscular VSD.