T. Lilaj et al., Influence of the preceding exchange on peritoneal equilibration test results: A prospective study, AM J KIDNEY, 34(2), 1999, pp. 247-253
The standard peritoneal equilibration test (PET) should be performed after
a long overnight dwell, which is easily possible in continuous ambulatory p
eritoneal dialysis patients. However, far such a procedure, patients underg
oing automated peritoneal dialysis or daily ambulatory peritoneal dialysis
have to change their regimen and, in the case of high peritoneal transport
rates, run the risk for fluid absorption, We compared dialysate to plasma r
atios (D/P) of creatinine, blood urea nitrogen (BUN), phosphate, sodium, to
tal protein, and albumin measured during PET after an 8- to Ii-hour dry per
iod (PET dry), after a preceding exchange with a long dwell time (PET stand
ard), and immediately after tidal peritoneal dialysis (PET tidal), D/P rati
os of creatinine, BUN, phosphate, and sodium at 2 and 4 hours were greater
during PET dry compared with both PET standard and PET tidal, The quotient
of dialysate glucose at 2 hours to dialysate glucose at time point 0 was si
gnificantly less in PET dry compared with both PET tidal and PET standard,
During the first 2 hours of PET, the increase of D/P curves of creatinine a
nd BUN, as well as phosphate, was significantly steeper in PET dry than PET
tidal and PET standard. DIP ratios of albumin and protein were greatest in
PET dry and least in PET tidal, There was a significant difference between
all three PETs at 0, 2, and 4 hours of dwell time. PET curves were signifi
cantly steeper during PET dry compared with PET tidal in case of D/P protei
n (during the first 2 hours of dwell time) and D/P albumin (during the enti
re dwell time). Similar differences between the PET curves of protein and a
lbumin were observed between PET dry and PET standard. These data clearly i
ndicate a dry period before PET significantly influences the DIP ratios of
small solutes, protein, and albumin measured during the test. (C) 1999 by t
he National Kidney Foundation, Inc.