Corneal endothelial changes in patients with chronic renal failure

PURPOSE: To; evaluate the morphologic changes of the corneal endothelium in patients with chronic renal failure, METHODS: Twenty corneas of 20 patients with chronic renal failure undergoin g hemodialysis were examined by wide-field specular microscopy. Twenty norm al corneas from 20 healthy age-matched subjects were enrolled as control co rneas, RESULTS: Despite normal endothelial cell density, the corneal endothelium o f patients with chronic renal failure showed marked polymegethism and pleom orphism, CONCLUSION: Polymegethism and pleomorphism of the corneal endothelium are f ound in patients with chronic renal failure, (C) 1999 by Elsevier Science I nc. All rights reserved.