A new point mutation of the androgen receptor gene in a patient with partial androgen resistance and severe oligozoospermia

Mutations of the androgen receptor gene in genetic males cause a variety of androgen insensitivity syndromes varying from female phenotype through int ersexuality to male phenotype with infertility. The identification of a mis sense mutation in the steroid-binding domain in an infertile male with mild features of androgen insensitivity is reported here.