Antiproliferative effects of a product isolated from the gorgonian Rumphella aggregata

Authors
Nourry, M Urvois, PA Tomasoni, C Biard, JF Verbist, JF Roussakis, C
Citation
M. Nourry et al., Antiproliferative effects of a product isolated from the gorgonian Rumphella aggregata, ANTICANC R, 19(3A), 1999, pp. 1881-1885
Citations number
7
Categorie Soggetti
Onconogenesis & Cancer Research
Journal title
ANTICANCER RESEARCH
ISSN journal
02507005 → ACNP
Volume
19
Issue
3A
Year of publication
1999
Pages
1881 - 1885
Database
ISI
SICI code
0250-7005(199905/06)19:3A<1881:AEOAPI>2.0.ZU;2-N
Abstract
A fraction isolated from the gorgonian Rumphella aggregata (Plexauridae) wa s studied vitro on asynchronous cells of a human non-small-cell-bronchopulm onary-carcinoma line (NSCLC- N6). Cell growth appeared to be inhibited in t he GI phase of the cell cycle, and kinetic studies in pretreated cells show ed that this growth arrest was irreversible. These events seem to show a te rminal maturation induced by this new product.