Xenotransplantability of human squamous cell lung cancer in nude mice is not affected by angiogenic factors

Authors
Mattern, J Koomagi, R Volm, M
Citation
J. Mattern et al., Xenotransplantability of human squamous cell lung cancer in nude mice is not affected by angiogenic factors, ANTICANC R, 19(3A), 1999, pp. 1941-1943
Citations number
10
Categorie Soggetti
Onconogenesis & Cancer Research
Journal title
ANTICANCER RESEARCH
ISSN journal
02507005 → ACNP
Volume
19
Issue
3A
Year of publication
1999
Pages
1941 - 1943
Database
ISI
SICI code
0250-7005(199905/06)19:3A<1941:XOHSCL>2.0.ZU;2-C
Abstract
Sixty-two human squamous cell lung carcinomas were analyzed for expression of various angiogenic growth factors and their receptors using immunohistoc hemistry. The data were correlated with xenotransplantability of these tumo rs in nude mice. None of the factors investigated did show an association w ith xenotransplantability. However, there was a trend that specimens lackin g VEGF165 were established as xenografts at a higher incidence (52%) than t hose expressing VEGF165 (39%).