The 28 kDa peroxiredoxin from rat exibited peroxidase activity only in the
presence of dithiothreitol. Both organic and nonorganic peroxidases were fo
und to be substrates for the 28-kDa peroxiredoxin activity. Analysis of the
protective antioxidant activity of the 28-kDa peroxiredoxin revealed that
it is accounted for by its peroxidase activity.