Disproportionation reaction of disulfides promoted by nitric oxide (NO) inthe presence of oxygen

Authors
Itoh, T Tsutsumi, N Ohsawa, A
Citation
T. Itoh et al., Disproportionation reaction of disulfides promoted by nitric oxide (NO) inthe presence of oxygen, BIOORG MED, 9(15), 1999, pp. 2161-2166
Citations number
17
Categorie Soggetti
Chemistry & Analysis
Journal title
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
ISSN journal
0960894X → ACNP
Volume
9
Issue
15
Year of publication
1999
Pages
2161 - 2166
Database
ISI
SICI code
0960-894X(19990802)9:15<2161:DRODPB>2.0.ZU;2-K
Abstract
Two disulfides brought about disproportionation reaction to afford an unsym metrical disulfide in 50% yield with a catalytic amount of nitric oxide in the presence of oxygen. The reaction proceeded faster when alkyl disulfides were employed for the reaction, and the substituent effects suggested that the reaction commenced with an oxidative process, (C) 1999 Elsevier Scienc e Ltd. All rights reserved.