Absence of mutations in the ATM gene in forty-seven cases of sporadic breast cancer

Citation
Dg. Bebb et al., Absence of mutations in the ATM gene in forty-seven cases of sporadic breast cancer, BR J CANC, 80(12), 1999, pp. 1979-1981
Citations number
33
Categorie Soggetti
Oncology,"Onconogenesis & Cancer Research
Journal title
BRITISH JOURNAL OF CANCER
ISSN journal
00070920 → ACNP
Volume
80
Issue
12
Year of publication
1999
Pages
1979 - 1981
Database
ISI
SICI code
0007-0920(199908)80:12<1979:AOMITA>2.0.ZU;2-J
Abstract
Epidemiological evidence points to an increased risk of breast cancer in at axia telangiectasia (AT) heterozygote women. Previous attempts to screen ea rly onset or familiar breast cancer patients failed to confirm an associati on. The issue of AT and late onset sporadic breast cancer remained unresolv ed. We screened 47 women who developed later onset, sporadic breast cancer for ataxia telangiectasia mutated (ATM) mutations. No mutations were found.