Because polyethylene wear adversely affects the outcome of total hip arthro
plasty, reliable techniques for in vivo radiographic evaluation of femoral
head penetration into the polyethylene liner are needed. With the recent de
velopment of software to measure three-dimensional femoral head penetration
, the adequacy of two-dimensional head penetration measurements to estimate
a three-dimensional process has been questioned. Thus, the purpose of the
current study was to compare directly two-dimensional and three-dimensional
radiographic measurements of femoral head penetration. Using two computer
assisted radiographic techniques, the authors of this study measured the tw
o-dimensional and the three-dimensional penetration of the femoral head int
o the polyethylene liner in 202 hips implanted with porous coated acetabula
r components. A comparison of two-dimensional and three-dimensional measure
ments showed that, on average, the mean amount of three-dimensional head pe
netration was larger than the mean amount of two-dimensional head penetrati
on. However, linear regression analysis showed that the two measurements we
re highly correlated (r(2) = 0.87, slope = 0.99, intercept = 0.08 mm), For
most patients (95%), two-dimensional and three-dimensional measurements of
femoral head penetration were nearly equal. However, there was a small subs
et of patients (5%) for whom three-dimensional radiographic penetration mea
surements were three times greater than corresponding two-dimensional radio
graphic penetration measurements. No common risk factor among this small su
bset of patients was identified. The current study provides practical infor
mation for the orthopaedic surgeon trying to assess polyethylene wear in hi
p replacement cases. It shows that for most patients head penetration can b
e measured sufficiently from anteroposterior radiographs alone. However, in
a small percentage of patients (5% in the current study) the femoral head
also moves perpendicular to the plane of the anteroposterior radiograph. Fo
r these cases, accurate analysis of head penetration requires three-dimensi
onal analysis using anteroposterior and lateral radiographs.