We have used an antisense retrovirus strategy to test the role of pl-integr
in in the early period of clone development in the embryonic chick neural r
etina. Analyses of clone size and dispersion demonstrated a marked effect o
f reducing the levels of expressed pl-integrin on this critical phase of re
tina cell and tissue development. (C) 1999 Elsevier Science B.V. All rights
reserved.