Papular-purpuric "gloves and socks" syndrome

In 1990, we first described the papular-purpuric "gloves and socks" syndrom e (PPGSS). It is characterized by an itching erythema and edema of the hand s and feet together with oral mucosal lesions and fever. The skin lesions s ubsequently become purpuric and resolve spontaneously after a few days. In more than half of the patients, an acute parvovirus B 19 infection has been proven. In a few cases of PPGSS, other viral infections have been found,fo r example hepatitis B and measles. We report on a patient with PPGSS and re view the literature.