This report emphasizes the application of behavior-genetic designs to
the study of sensitivity to toxic chemicals, and features of multiple
chemical sensitivity and substance abuse that are polar opposites. The
implications of these issues for future research are discussed in rel
ation to twin, adoption, and sibling pair studies, as well as in relat
ion to the degree to which genetically selected lines of rodents that
have been developed in the alcoholism field are applicable to multiple
chemical sensitivity.