Application of molecular topology to liquid viscosity prediction for a group of organic compounds

Molecular Topology has been applied to search for a mathematical model able to predict liquid viscosity values for an extensive group of organic compo unds with C, H, O, N, S and halogenous atoms. The topological descriptors w e have used are the connectivity indices from Kier et Hall -up to fourth or der-, and the electrotopological indices. Quality of regression equation fi nally selected has been evaluated by a crossvalidation study.. Viscosity of ail compounds excepted 1,1,2-trichlorotrifluoro etane is correctly predict ed by the model proposed.