Nonlinear recursive feedback control for the regulation of substrate concentration in a fixed bed bioreactor

In this work, a recursive nonlinear feedback control law for the regulation of the outlet substrate concentration for a fixed bed bioreactor with immo bilized biomass is designed. The control algorithm is based on a reduced or der model related with ordinary differential equations and only made use of a discrete substrate outlet concentration for its implementation. It is sh own that the proposed control algorithm is robust against disturbances in t he input substrate concentration. The performance of the proposed regulatio n scheme is illustrated by means of numerical simulations. (C) 1999 Society of Chemical Industry.