Electrical neuromodulation for disabling angina pectoris related to isolated stenoses of small epicardial coronary arteries

Patients with symptomatic small vessel coronary artery disease may be inade quate candidates for revascularization procedures. They may suffer from ref ractory angina, which does not respond to maximal anti-anginal drug therapy . In addition to patients with end stage coronary artery disease and syndro me X, this newly defined group of subjects with an isolated stenosis of a s mall coronary artery may benefit from electrical neurostimulation. We descr ibe two patients with intractable angina caused by a significant narrowing of a diagonal branch. This treatment modality should be considered as an al ternative method for unsatisfactory revascularization procedures.