Musculoskeletal manifestations of the Antley-Bixler syndrome

The Antley-Bixler syndrome is a rare disorder with many musculoskeletal ano malies that demand orthopedic assessment. The syndrome includes skeletal, c raniofacial, and urogenital anomalies. The most common skeletal deformities are radiohumeral synostosis, craniosynostosis, multiple joint contractures , and arachnodactyly. Other orthopedic manifestations that may occur are fe moral bowing, ulnar bowing, camptodactyly, synostoses of carpal and tarsal bones, clubfoot, vertebral body anomalies, perinatal fractures, and advance d skeletal age. The inheritance pattern is thought to be autosomal recessiv e. A patient with this syndrome is described, which is the 18th of 24 repor ts published in the world literature. This case is compared with the other reported cases.