Eosinophilic granuloma of bone: Results of treatment with curettage, cryosurgery, and bone grafting

Intralesional instillation of steroids is currently the first choice of tre atment for eosinophilic granuloma of bone. However, some lesions fail to re spond or are unsuitable for injection therapy due location, pending patholo gic fracture, and soft tissue intrusion. The authors treated six patients w ith these lesion characteristics using curettage, cryosurgery, and bone gra fting. After a mean follow-up of 34.3 months, all lesions healed completely , although one femoral fracture occurred 8 months after the operation. In s elected cases of eosinophilic granuloma of bone, a primary surgical treatme nt seems feasible. The use of cryosurgery as adjuvant treatment extends the surgical margin and is of value in averting local recurrence.