Z. Tannous et al., Syringolymphoid hyperplasia and follicular mucinosis in a patient with cutaneous T-cell lymphoma, J AM ACAD D, 41(2), 1999, pp. 303-308
Springolymphoid hyperplasia with alopecia is an uncommon chronic dermatosis
of which 9 cases have been reported, with or without follicular mucinosis
or cutaneous T-cell lymphoma. We report a patient with cutaneous T-cell lym
phoma and syringolymphoid hyperplasia and follicular mucinosis and review t
he previously reported cases. All reported cases with syringolymphoid hyper
plasia were men (10 of 10), with the clinical findings of alopecia (9 of 10
) and anhidrosis (3 of 10). Only 3 of 10 cases had associated follicular mu
cinosis, Of the 7 cases investigated, 6 were found to hve cutaneous T-cell
lymphoma. Three patients were not investigated for cutaneous T-cell lymphom
a. Although syringolymphoid hyperplasia can be idiopathic, it can also refl
ect a syringotropic cutaneous T-cell lymphoma. Careful follow-up with a bio
psy of persistent lesions is recommended to evaluate for the presence of ly
mphoma.