Syringolymphoid hyperplasia and follicular mucinosis in a patient with cutaneous T-cell lymphoma

Springolymphoid hyperplasia with alopecia is an uncommon chronic dermatosis of which 9 cases have been reported, with or without follicular mucinosis or cutaneous T-cell lymphoma. We report a patient with cutaneous T-cell lym phoma and syringolymphoid hyperplasia and follicular mucinosis and review t he previously reported cases. All reported cases with syringolymphoid hyper plasia were men (10 of 10), with the clinical findings of alopecia (9 of 10 ) and anhidrosis (3 of 10). Only 3 of 10 cases had associated follicular mu cinosis, Of the 7 cases investigated, 6 were found to hve cutaneous T-cell lymphoma. Three patients were not investigated for cutaneous T-cell lymphom a. Although syringolymphoid hyperplasia can be idiopathic, it can also refl ect a syringotropic cutaneous T-cell lymphoma. Careful follow-up with a bio psy of persistent lesions is recommended to evaluate for the presence of ly mphoma.