Hc. Nousari et al., Generalized lupus erythematosus profundus in a patient with genetic partial deficiency of C4, J AM ACAD D, 41(2), 1999, pp. 362-364
Lupus erythematosus profundus (LEP) is an unusual variant of cutaneous lupu
s erythematosus (CLE)that is characterized by chronic, recurrent inflammati
on of the subcutaneous tissue leading to fibrosis. It is found in the setti
ngs of both discoid and systemic lupus erythematosus. Generalized forms are
extremely rare. We present a case of generalized LEP associated with genet
ic partial C4-deficiency.