Transition structures of intramolecular ene reactions in the presence of activating substituents: a theoretical study

Authors
Das, GK
Citation
Gk. Das, Transition structures of intramolecular ene reactions in the presence of activating substituents: a theoretical study, J CHEM S P2, (8), 1999, pp. 1779-1782
Citations number
21
Categorie Soggetti
Physical Chemistry/Chemical Physics
Journal title
JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 2
ISSN journal
03009580 → ACNP
Issue
8
Year of publication
1999
Pages
1779 - 1782
Database
ISI
SICI code
0300-9580(199908):8<1779:TSOIER>2.0.ZU;2-T
Abstract
Transition states of intramolecular ene reactions in the presence of an act ivating substituent were studied by an AM1 approximation to calculate the p roportion of various diastereomeric products. The predicted diastereoselect ivity for the formation of a five membered ring containing chiral and/or ac hiral centres was found to be in good agreement with the reported experimen tal observations.