Supplementary report on experimental autumn crocus (Colchicum autumnale L.) poisoning in cattle: Morphological evidence of apoptosis

Previously we reported that tissue destruction characterized by the presenc e of karyopyknotic, karyorrhectic and mitotically arrested cells was seen i n alimentary epithelial cells and lymphocytes in the lymphoid and hemopoiet ic systems of cattle experimentally administered with autumn crocus (Colchi cum autumnale L.). This report deals with the mechanism of acute cellular i njury following experimental autumn crocus poisoning in cattle as demonstra ted by the in situ DNA strand break analysis and electron microscopy. The a nalyses revealed that cellular injury caused by autumn crocus was closely a ssociated with apoptosis.