Purpose: The purpose of this study was to identify rates of diagnosis-speci
fic musculoskeletal injuries in U.S. Marine Corps recruits and to examine t
he association between patterns of physical training and these injuries. Me
thods: Subjects were 1,296 randomly selected male Marine recruits, ages 17
to 28 yr, who reported to Marine Corps Recruit Depot San Diego for boot cam
p training between January 12 and September 14, 1993. Recruits were followe
d prospectively through 12 wk of training for injury outcomes. Injury patte
rns were examined in relation to weekly volumes and types of vigorous physi
cal training. Results: The overall injury rate was 39.6% (number of recruit
s injured/population at risk), with 82% of injuries occurring in the lower
extremities. Overuse injuries accounted for 78% of the diagnoses. The most
frequent site of injury was the ankle/foot region (34.3% of injuries), foll
owed by the knee (28.1%). Ankle sprains (6.2%, N = 1,143), iliotibial band
syndrome (5.3%, N = 1,143), and stress fractures (4.0%, N = 1,296) were the
most common diagnoses. Injury rates were highest during the weeks with hig
h total volumes of vigorous physical training and the most hours of running
and matching. Weekly injury rates were significantly correlated with hours
of vigorous physical training (overuse injuries r = 0.667, P = 0.018; acut
e injuries r = 0.633, P = 0.027). Conclusions: The results of this controll
ed epidemiological investigation indicate that volume of vigorous physical
training may be an etiologic factor for exercise-related injuries. The find
ings also suggest that type of training, particularly running, and abrupt i
ncreases in training volume may further contribute to injury risk.