Mucosal immunization with DNA vaccines

Authors
McCluskie, MJ Davis, HL
Citation
Mj. Mccluskie et Hl. Davis, Mucosal immunization with DNA vaccines, MICROBES IN, 1(9), 1999, pp. 685-698
Citations number
145
Categorie Soggetti
Immunology
Journal title
MICROBES AND INFECTION
ISSN journal
12864579 → ACNP
Volume
1
Issue
9
Year of publication
1999
Pages
685 - 698
Database
ISI
SICI code
1286-4579(199907)1:9<685:MIWDV>2.0.ZU;2-I
Abstract
DNA vaccines can induce potent humoral and cellular immune responses in num erous animal models. Most DNA vaccines have been administered parenterally; however, more effective protection against mucosal pathogens could be achi eved with mucosal immunization. This review concentrates on the use of DNA vaccines for the induction of mucosal immunity. (C) Elsevier, Paris.