Roles of lipoarabinomannan in the pathogenesis of tuberculosis

Tuberculosis is a worldwide public health threat caused by Mycobacterium tu berculosis. All mycobacteria express a unique cell envelope glycolipid, lip oarabinomannan, which can be released at sites of infection. Lipoarabinoman nan is a potential virulence factor which ran bind to leukocytes and modula te immune responses. Here, we provide an overview of the interactions of my cobacteria and lipoarabinomannan with immune cells. (C) Elsevier, Paris.