Advances in diagnosis, treatment and prognosis of intracerebral tuberculomas in the last 50 years - Report of 21 cases

Intracranial tuberculosis accounts for less than 0.2 % of intracranial spac e-occupying lesions diagnosed and treated in western countries, while it st ill represents a major neurosurgical finding in underdeveloped countries. The introduction of chemotherapic agents for the treatment of tubercular in fection, as well as the general improvement in the socio-economic status of the population as a whole, have both played an important role in the drama tic reduction of intracranial tuberculomas in industrialized countries. The increasing migration flow from third world countries, along with other factors, will probably result in increased exposure to such pathologies als o in western Neurosurgical centers. A series of intracranial tuberculoma lesions were selected and analyzed, wi th the aim of pointing out the evolution of diagnosis, treatment and progno sis of such clinical entities throughout the years.