Application of CR-39 for alpha autoradiography and in vivo detection of B-10 accumulations in tumor bearing mice

It is required to achieve an accurate measurement of B-10 distributions and concentrations in the turner cells for baron neutron capture therapy (BNCT ). We employed a technique of neutron capture autoradiography (NCAR) of the whole body samples of tumor bearing mice using CR-39 plastic track detecto rs to the measurements of B-10 accumulations in mice. In order to confirm t he validity of the NCAR measurements, the differential REL spectrum for the neutron-induced particles emitted from the standard filter paper sheets wa s compared with that for B-10-compound solution. Differential REL spectrum far protons. originated from the biogenically abundant nuclides through N-1 4 (n, p) C-14 and H-1 (n, n') H-1 reactions was measured in vivo using a sm all piece of CR-39 inserted into the tumor of mouse.