TC-99M-MIBI PRONE SCINTIMAMMOGRAPHY IN PATIENTS WITH HIGH AND INTERMEDIATE RISK MAMMOGRAPHY

Mammographic lesions can be classified into categories of high (HR), i ntermediate (IR) and low risk of breast cancer. We have performed Tc-9 9m MIBI scintimammography on 85 patients with high or intermediate ris k lesions in order to verify its ability to diagnose cancer before bio psy. The scintimammography was performed in prone lateral view; all th e patients were submitted to excisional biopsy. HR lesions showed 86% of cancers and scintigraphic accuracy of 0.81. The accuracy of scintim ammography was 0.97 in lesions larger than 1 cm. IR lesions showed 47% of cancel with scintigraphic accuracy of 0.95. The scintigraphic sens itivity was 0.97 lesions larger than and 0.50 in lesion smaller than 1 cm, whereas the specificity was always about 90%. Out results suggest that scintimammography can substantially decrease the need of biopsy for breast cancel diagnosis.