Agricultural productivity is severely affected by soil salinity, One possib
le mechanism by which plants could survive salt stress is to compartmentali
ze sodium ions away from the cytosol. Overexpression of a vacuolar Na+/H+ a
ntiport from Arabidopsis thaliana in Arabidopsis plants promotes sustained
growth and development in soil watered with up to 200 millimolar sodium chl
oride. This salinity tolerance was correlated with higher-than-normal level
s of AtNHX1 transcripts, protein, and vacuolar Na+/H+ (sodium/proton) antip
ort activity, These results demonstrate the feasibility of engineering salt
tolerance in plants.