The development of large area Position Sensitive Photo Multiplier Tube
s (PSPMT) by Hamamatsu is opening new imaging possibilities in Nuclear
Medicine. In particular the realization of the 8'' PSPMT prototype re
presents the first imporitant technological advantage since the discov
ery of the Anger Camera. PSPMT virtually integrates in one hundreds PM
T allowing the creation of dedicated detectors. A Single Tube Gamma Ca
mera based on a 5'' PSPMT dedicated to scintimammography is presented
and discussed in this work. To optimize gamma camera response two diff
erent scintillating arrays were tested: YAP:Ce and CsI (Tl). Their ove
rall size cover all photocathode active al ea, and crystal pixel size
was 2 mm x 2 mm. The defection efficiency was comparable to that of An
ger Camera. The best result was obtained by CsI (Tl) scintillating: an
intrinsic spatial Resolution of 1.6 mm FWHM and a relative energy res
olution of 17% FWHM New image possibilities in scintimammography are o
ffered by Single Tube Gamma Camera operating in the same radiological
projection of RX mammography.