NMR characterization of novel purine nucleoside analogues with 2,3-epoxypropyl or 3-amino-2-hydroxypropyl moiety

The structures of the title compounds were determined from their H-1 and C- 13 NMR on the basis of chemical shifts, substituent induced shifts, H-H and C-H coupling constants, as well as connectivities in COSY, NOESY and HETCO R spectra. It has been established that the purine skeleton is substituted at either N-9 or both N-9 and N-6 positions.