Asymmetric synthesis of 1,2-and 1,4-dihydroquinolines

Authors
Rezgui, F Mangeney, P Alexakis, A
Citation
F. Rezgui et al., Asymmetric synthesis of 1,2-and 1,4-dihydroquinolines, TETRAHEDR L, 40(34), 1999, pp. 6241-6244
Citations number
16
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
40
Issue
34
Year of publication
1999
Pages
6241 - 6244
Database
ISI
SICI code
0040-4039(19990820)40:34<6241:ASO11>2.0.ZU;2-7
Abstract
Asymmetric synthesis of dihydroquinolines by addition of organometallic rea gents on a chiral 3-quinolinyl aminal was studied. 1,2-Adducts were obtaine d with good regio- and diastereoselectivity. The absolute configuration for 1,2-adducts was determined by X-ray analysis and for 1,4-adducts by chemic al correlation. (C) 1999 Published by Elsevier Science Ltd. All rights rese rved.