Transfer RNAs and pathogenicity islands

Authors
Hou, YM
Citation
Ym. Hou, Transfer RNAs and pathogenicity islands, TRENDS BIOC, 24(8), 1999, pp. 295-298
Citations number
27
Categorie Soggetti
Biochemistry & Biophysics
Journal title
TRENDS IN BIOCHEMICAL SCIENCES
ISSN journal
09680004 → ACNP
Volume
24
Issue
8
Year of publication
1999
Pages
295 - 298
Database
ISI
SICI code
0968-0004(199908)24:8<295:TRAPI>2.0.ZU;2-0
Abstract
The tRNAs are central components in translation. In addition, they are esse ntial for replication of retroviruses: tRNAs bind to viral genomes through their 3'-end sequences and act as primers for initiation of viral replicati on. Here, I discuss the possibility that tRNAs also play a role in the hori zontal transfer of bacterial pathogenicity islands between different pathog ens. Such a role would implicate tRNAs in DNA recombination.