Marijuana has been shown to be one of the commonly abused substances in the
world, especially among teenagers and young adults. Although its addictive
potential and psychomotor side-effects have been widely publicized, the is
sue of possible carcinogenicity is not as well perceived. Marijuana smoke c
ontains many of the same organic and inorganic compounds that are carcinoge
ns, co-carcinogens, or tumor promoters found in tobacco smoke. We have enco
untered several young marijuana users with no history of tobacco smoking or
other significant risk factors who were diagnosed to have lung or other ae
ro digestive cancers in our practice. Although there are several experiment
al and epidemiological studies suggesting an association of marijuana use a
s a possible cause of cancers, this issue remains controversial. It is hope
d that our case presentation can help to stimulate further awareness and re
search into this issue.