Myelolipomas of the adrenal gland were first described in 1905. They are ra
re cortical, nonfunctioning, benign neoplasms, generally unilateral, usuall
y discovered by accident or at autopsy. Thus they are often classified as '
incidentaloma'. These tumors are more frequent in males 40-60 years old. Mo
st adrenal myelolipomas are small (diameter < 4 cm) and asymptomatic (70%),
but larger tumors may cause local symptoms secondary to mechanical compres
sion. Very large bilateral adrenal myelolipomas are exceedingly rare. They
generally require no treatment; however, if symptomatics or if diagnosis is
in doubt, surgery is needed. Usually only monolateral adrenalectomy is per
formed, even in the presence of bilateral tumors, to preserve adrenal funct
ion. We present a case of bilateral, symptomatic giant myelolipoma in a you
ng woman, treated with bilateral adrenalectomy.