Autonomic regulation in patients with panic attacks according to data of longitudinal investigation of heart rhythm variability

During a repeated study in recumbent position as well as during 48-hour mon itoring of the indices of variability of RR-intervals of ECC (MDRR) in pati ents with panick attacks (PA) a stable dominance of VLF (0,07-0,01 Hz) and regidity of the spectrum typical for patients with panic attacks (PA) in pe riod between the attacks was found. Prevalence of fear emotions as well as accompanying hypothalamic insufficiency were also associated with a decreas e of HF. In prodromic period, in attack and after it, there was no dynamics in the frequency of heart's contractions, but there was a sharp increase o f MDRR. In prodromic period VLF and LF considerably increased, while HF dec reased. In a moment of a panic attack LF and HF continued to increase, whil e VLF significantly lowered. Activation of vasomotor (LF), vagal (HF) and c erebral (VLF) mechanisms was maintained during 5 minutes of the study after PA completion with a clear predominance of LF component.