Automated stereotactic core needle biopsy of microcalcifications with correlation to surgical biopsy

Purpose: To compare pathologic findings from stereotactic core and excision al biopsies in patients with microcalcifications in the breast. Material and Methods: Stereotactic core needle biopsies of 101 lesions with mammographic evidence of microcalcifications were performed with long-thro w (2.2 cm) automated core biopsy devices fitted with 2.1-mm needles. The co re specimens were placed on microscope slides and radiographed. The patholo gic features of core and excisional specimens were compared. Results: In 100 of the 101 breast lesions, a correct choice for an addition al diagnostic procedure or definitive treatment could have been made upon h istopathologic findings of the core needle biopsy. Conclusion: Stereotactic core needle biopsy is a reliable alternative to su rgical biopsy of breast lesions with microcalcifications provided that spec imen radiography has been performed to ensure that appropriate tissue has b een obtained. Excisional biopsy may be avoided if microcalcifications are v isible in radiographs of core biopsy specimen with benign histology.